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1

Selective antagonization of activated Nrf2 and inhibition of cancer cell proliferation by procyanidins from Cinnamomi Cortex extract

Ohnuma, Tomokazu, Anzai, Eri, Suzuki, Yohei, Shimoda, Mai, Saito, Shin, Nishiyama, Takahito, Ogura, Kenichiro, Hiratsuka, Akira

Journal:

Archives of Biochemistry and Biophysics

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

2

A Low-Spin Ruthenium(IV)–Oxo Complex: Does the Spin State Have an Impact on the Reactivity?

Prof. Dr. Takahiko Kojima, Yuichirou Hirai, Dr. Tomoya Ishizuka, Dr. Yoshihito Shiota, Prof. Dr. Kazunari Yoshizawa, Dr. Kenichiro Ikemura, Prof. Dr. Takashi Ogura, Prof. Dr. Shunichi Fukuzumi

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 464 KB

english, 2010

3

Suiphotransferase-mediated covalent binding of the carcinogen 7,12-dihydroxymethylbenz to calf thymus DNA and its inhibition by glutatbione transferase

Watabe, Tadashi, Hiratsuka, Akira, Ogura, Kenichiro

Journal:

Year:

1987

Language:

english

File:

PDF, 1.00 MB

english, 1987

4

Multivariate approach to on-line supercritical fluid extraction â supercritical fluid chromatography - mass spectrometry method development

Wicker, A. Paige, Tanaka, Kenichiro, Nishimura, Masayuki, Chen, Vivian, Ogura, Tairo, Hedgepeth, William, Schug, Kevin A.

Journal:

Analytica Chimica Acta

Year:

2020

File:

PDF, 2.17 MB

2020

5

A Low-Spin Ruthenium(IV)–Oxo Complex: Does the Spin State Have an Impact on the Reactivity?

Prof. Dr. Takahiko Kojima, Yuichirou Hirai, Dr. Tomoya Ishizuka, Dr. Yoshihito Shiota, Prof. Dr. Kazunari Yoshizawa, Dr. Kenichiro Ikemura, Prof. Dr. Takashi Ogura, Prof. Dr. Shunichi Fukuzumi

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

6

Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3

Haruka Nishimuta, Hisakazu Ohtani, Masayuki Tsujimoto, Kenichiro Ogura, Akira Hiratsuka, Yasufumi Sawada

Journal:

Biopharmaceutics & Drug Disposition

Year:

2007

Language:

english

File:

PDF, 175 KB

english, 2007

7

Molecular Toxicological Mechanism of the Lethal Interactions of the New Antiviral Drug, Sorivudine, with 5-Fluorouracil Prodrugs and Genetic Deficiency of Dihydropyrimidine Dehydrogenase

Tadashi Watabe, Kenichiro Ogura, Takahito Nishiyama

Journal:

Year:

2002

File:

PDF, 27 KB

2002

8

Organic anion–transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice

Iván L. Csanaky, Hong Lu, Youcai Zhang, Kenichiro Ogura, Supratim Choudhuri, Curtis D. Klaassen

Journal:

Year:

2011

Language:

english

File:

PDF, 713 KB

english, 2011

9

Naftopidil, a selective α-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest

Hideki Kanda, Kenichiro Ishii, Yuji Ogura, Tetsuya Imamura, Masahiro Kanai, Kiminobu Arima, Yoshiki Sugimura

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

10

Rat Liver Theta-Class GlutathioneS-Transferases T1-1 and T2-2: Their Chromatographic, Electrophoretic, Immunochemical, and Functional Properties

Akira Hiratsuka, Takeshi Nishijima, Haruhiro Okuda, Kenichiro Ogura, Tadashi Watabe

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 448 KB

english, 1997

11

Synchrotron-radiation-excited etching of SiC

Masayoshi Ogura, Shingo Terakado, Shigeo Suzuki, Kenichiro Tanaka

Journal:

Applied Surface Science

Year:

1994

Language:

english

File:

PDF, 479 KB

english, 1994

12

Synthesis and odor of optically active 2-n-hexyl- and 2-n-heptylcyclopentanone and the corresponding δ-lactones

Takeshi Yamamoto, Miharu Ogura, Akira Amano, Kenichiro Adachi, Toshimitsu Hagiwara, Tsuneyoshi Kanisawa

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 78 KB

english, 2002

13

Inhibitory Effects of Various Beverages on Ritodrine Sulfation by Recombinant Human Sulfotransferase Isoforms SULT1A1 and SULT1A3

Haruka Nishimuta, Masayuki Tsujimoto, Kenichiro Ogura, Akira Hiratsuka, Hisakazu Ohtani, Yasufumi Sawada

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 372 KB

english, 2005

14

Improvement in predicting tumorigenic phenotype of androgen-insensitive human LNCaP prostatic cancer cell subline in recombination with rat urogenital sinus mesenchyme

Masahiro Kanai, Kenichiro Ishii, Hideki Kanda, Yuji Ogura, Hideaki Kise, Kiminobu Arima, Yoshiki Sugimura

Journal:

Year:

2008

Language:

english

File:

PDF, 420 KB

english, 2008

15

Bisphenol A induces permanent squamous change in mouse prostatic epithelium

Yuji Ogura, Kenichiro Ishii, Hideki Kanda, Masahiro Kanai, Kiminobu Arima, Yuzhuo Wang, Yoshiki Sugimura

Journal:

Differentiation

Year:

2007

Language:

english

File:

PDF, 4.13 MB

english, 2007

16

Efficient method for a one-carbon homologation of aldehydes and benzophenone to carboxylic acids

Takahashi, Kazumasa, Shibasaki, Kenichiro, Ogura, Katsuyuki, Iida, Hirotada

Journal:

Journal of Organic Chemistry

Year:

1983

Language:

english

File:

PDF, 544 KB

english, 1983

17

Effect of the Axial Ligand on the Reactivity of the Oxoiron(IV) Porphyrin π-Cation Radical Complex: Higher Stabilization of the Product State Relative to the Reactant State

Takahashi, Akihiro, Yamaki, Daisuke, Ikemura, Kenichiro, Kurahashi, Takuya, Ogura, Takashi, Hada, Masahiko, Fujii, Hiroshi

Journal:

Inorganic Chemistry

Year:

2012

Language:

english

File:

PDF, 1.57 MB

english, 2012

18

The Impact of Gender Difference on the Effects of Preinfarction Angina on Microvascular Damage With Reperfused Myocardial Infarction

Shinobu Hosokawa, Yoshikazu Hiasa, Naotsugu Murakami, Yohei Tobbeto, Takafumi Nakagawa, Pomin Chen, Shin-ichiro Miyazaki, Riyo Ogura, Keitaro Mahara, Hitoshi Miyajima, Kenichiro Yuba, Takefumi Takahas

Journal:

Clinical Cardiology

Year:

2010

Language:

english

File:

PDF, 157 KB

english, 2010

19

The effects of atorvastatin on coronary endothelial function in patients with recent myocardial infarction

Shinobu Hosokawa, Yoshikazu Hiasa, Takeshi Tomokane, Riyo Ogura, Hitoshi Miyajima, Yoshikazu Ohara, Tatsuro Ogata, Kenichiro Yuba, Naoki Suzuki, Takefumi Takahashi, Koichi Kishi, Ryuji Ohtani

Journal:

Clinical Cardiology

Year:

2006

Language:

english

File:

PDF, 492 KB

english, 2006

20

Molecular cloning and functions of rat liver hydroxysteroid sulfotransferases catalysing covalent binding of carcinogenic polycyclic arylmethanols to DNA

Tadashi Watabe, Kenichiro Ogura, Masahiro Satsukawa, Haruhiro Okuda, Akira Hiratsuka

Journal:

Chemico-Biological Interactions

Year:

1994

Language:

english

File:

PDF, 1.13 MB

english, 1994

21

Major hydroxysteroid sulfotransferase STa in rat liver cytosol may consist of two microheterogeneous subunits

Kenichiro Ogura, Masahiro Satsukawa, Haruhiro Okuda, Akira Hiratsuka, Tadashi Watabe

Journal:

Chemico-Biological Interactions

Year:

1994

Language:

english

File:

PDF, 960 KB

english, 1994

22

Usefulness of coronary flow reserve immediately after primary coronary stenting in predicting wall motion recovery in patients with anterior wall acute myocardial infarction

Takefumi Takahashi, Yoshikazu Hiasa, Yoshikazu Ohara, Koji Yamaguchi, Takeshi Tomokane, Riyo Ogura, Tatsuro Ogata, Kenichiro Yuba, Naoki Suzuki, Shinobu Hosokawa, Koichi Kishi, Ryuji Ohtani

Journal:

The American Journal of Cardiology

Year:

2004

Language:

english

File:

PDF, 181 KB

english, 2004

23

Usefulness of Ultrasonic Strain Measurements to Predict Regional Wall Motion Recovery in Patients With Acute Myocardial Infarction After Percutaneous Coronary Intervention

Yoshikazu Ohara, Yoshikazu Hiasa, Shinobu Hosokawa, Shinichiro Miyazaki, Riyo Ogura, Hitoshi Miyajima, Kenichiro Yuba, Naoki Suzuki, Takefumi Takahashi, Koichi Kishi, Ryuji Ohtani

Journal:

The American Journal of Cardiology

Year:

2007

Language:

english

File:

PDF, 662 KB

english, 2007

24

Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4

Teppei Kaku, Kenichiro Ogura, Takahito Nishiyama, Tomokazu Ohnuma, Kei Muro, Akira Hiratsuka

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

25

Involvement of SULT1A3 in elevated sulfation of 4-hydroxypropranolol in Hep G2 cells pretreated with β-naphthoflavone

Junko Miyano, Shigeo Yamamoto, Nobumitsu Hanioka, Shizuo Narimatsu, Tsutomu Ishikawa, Kenichiro Ogura, Tadashi Watabe, Masuhiro Nishimura, Nobuhiko Ueda, Shinsaku Naito

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 316 KB

english, 2005

26

Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4

Kenichiro Ogura, Yuko Ishikawa, Teppei Kaku, Takahito Nishiyama, Tomokazu Ohnuma, Kei Muro, Akira Hiratsuka

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 442 KB

english, 2006

27

Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound

Tomokazu Ohnuma, Shinji Nakayama, Eisaburo Anan, Takahito Nishiyama, Kenichiro Ogura, Akira Hiratsuka

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 926 KB

english, 2010

28

Reverse geometrical selectivity in glucuronidation and sulfation of cis- and trans-4-hydroxytamoxifens by human liver UDP-glucuronosyltransferases and sulfotransferases

Takahito Nishiyama, Kenichiro Ogura, Hiroaki Nakano, Tomokazu Ohnuma, Teppei Kaku, Akira Hiratsuka, Kei Muro, Tadashi Watabe

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 296 KB

english, 2002

29

Guinea Pig Liver Mu-Class GlutathioneS-Transferase M1-2 Cross-Reacts with Antibodies to both Rat Mu- and Theta-Class GlutathioneS-Transferases

Akira Hiratsuka, Kenichiro Ogura, Hiroyuki Fujioka, Yasuhiro Sakamoto, Haruhiro Okuda, Kouji Wada, Teruji Tanaka, Takahito Nishiyama, Tadashi Watabe

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 671 KB

english, 1998

30

Full-Length cDNA Cloning and Genomic Organization of the Mouse Liver-Specific Organic Anion Transporter-1 (lst-1)

Kenichiro Ogura, Supratim Choudhuri, Curtis D. Klaassen

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 206 KB

english, 2000

31

Cloning of the Full-Length Coding Sequence of Rat Liver-Specific Organic Anion Transporter-1 (rlst-1) and a Splice Variant and Partial Characterization of the Rat lst-1 Gene

Supratim Choudhuri, Kenichiro Ogura, Curtis D. Klaassen

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 305 KB

english, 2000

32

Cloning, Expression, and Ontogeny of Mouse Organic Anion-Transporting Polypeptide-5, a Kidney-Specific Organic Anion Transporter

Supratim Choudhuri, Kenichiro Ogura, Curtis D. Klaassen

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 181 KB

english, 2001

33

Cloning, Expression, and Ontogeny of Mouse Organic Anion-Transporting Polypeptide-5, a Kidney-Specific Organic Anion Transporter: Volume 280, Number 1 (2001), pages 92–98

Supratim Choudhuri, Kenichiro Ogura, Curtis D. Klaassen

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

File:

PDF, 11 KB

2001

34

Genomic Organization and Tissue-Specific Expression of Splice Variants of Mouse Organic Anion Transporting Polypeptide 2

Kenichiro Ogura, Supratim Choudhuri, Curtis D. Klaassen

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 264 KB

english, 2001

35

A reactive hydroxymethyl sulfate ester formed regioselectively from the carcinogen, 7,12-dihydroxymethylbenz[a]anthracene, by rat liver sulfotransferase

Tadashi Watabe, Akira Hiratsuka, Kenichiro Ogura, Kazushi Endoh

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 368 KB

english, 1985

36

Regioselective glutathione conjugation of the carcinogen, 7,12-dihydroxymethylbenz[α]anthracene, via reactive 7-hydroxymethyl sulfate ester in rat liver cytosol

Tadashi Watabe, Akira Hiratsuka, Kenichiro Ogura

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 411 KB

english, 1986

37

Long-chained 1-mercapto-n-alkanes as potent inhibitors toward liver alcohol dehydrogenase

Kiyoshi Miwa, Haruhiro Okuda, Kenichiro Ogura, Tadashi Watabe

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 362 KB

english, 1987

38

Cloning and sequence analysis of a rat liver cDNA encoding hydroxysteroid sulfotransferase

Kenichiro Ogura, Jiro Kajita, Hiroyuki Narihata, Tadashi Watabe, Shogo Ozawa, Kiyoshi Nagata, Yasushi Yamazoe, Ryuichi Kato

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 557 KB

english, 1989

39

cDNA Cloning of the hydroxysteroid sulfotransferase STa sharing a strong homology in amino acid sequence with the senescence marker protein SMP-2 in rat livers

Kenichiro Ogura, Jiro Kajita, Hiroyuki Narihata, Tadashi Watabe, Shogo Ozawa, Kiyoshi Nagata, Yasushi Yamazoe, Ryuichi Kato

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 480 KB

english, 1990

40

Molecular cloning and amino acid sequencing of rat liver class theta glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters of carcinogenic arylmethanols

Kenichiro Ogura, Takahito Nishiyama, Takahito Okada, Jiro Kajita, Hiroyuki Narihata, Tetsuro Watabe, Akira Hiratsuka, Tadashi Watabe

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 473 KB

english, 1991

41

The carcinogen, 7-hydroxymethyl-12-methylbenz[a]anthracene, is activated and covalently binds to DNA via a sulphate ester

Watabe Tadashi, Fujieda Toshiko, Hiratsuka Akira, Ishizuka Tsuneo, Hakamata Yoshiki, Ogura Kenichiro

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 528 KB

english, 1985

42

Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the C-glucuronidation of phenylbutazone

Takahito Nishiyama, Tomihiro Kobori, Kouji Arai, Kenichiro Ogura, Tomokazu Ohnuma, Kazuo Ishii, Kenichiro Hayashi, Akira Hiratsuka

Journal:

Archives of Biochemistry and Biophysics

Year:

2006

Language:

english

File:

PDF, 354 KB

english, 2006

43

Amino acid positions 69–132 of UGT1A9 are involved in the C-glucuronidation of phenylbutazone

Takahito Nishiyama, Miki Fujishima, Yasuhiro Masuda, Tadashi Izawa, Tomokazu Ohnuma, Kenichiro Ogura, Akira Hiratsuka

Journal:

Archives of Biochemistry and Biophysics

Year:

2008

Language:

english

File:

PDF, 211 KB

english, 2008

44

Induction of antioxidant and phase 2 drug-metabolizing enzymes by falcarindiol isolated from Notopterygium incisum extract, which activates the Nrf2/ARE pathway, leads to cytoprotection against oxidative and electrophilic stress

Tomokazu Ohnuma, Takao Komatsu, Shinji Nakayama, Takahito Nishiyama, Kenichiro Ogura, Akira Hiratsuka

Journal:

Archives of Biochemistry and Biophysics

Year:

2009

Language:

english

File:

PDF, 406 KB

english, 2009

45

UDP-glucuronosyltransferases 1A6 and 1A10 catalyze reduced menadione glucuronidation

Takahito Nishiyama, Tomokazu Ohnuma, Yuu Inoue, Takehiko Kishi, Kenichiro Ogura, Akira Hiratsuka

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

46

Cooperation of NAD(P)H:quinone oxidoreductase 1 and UDP-glucuronosyltransferases reduces menadione cytotoxicity in HEK293 cells

Takahito Nishiyama, Tadashi Izawa, Mami Usami, Tomokazu Ohnuma, Kenichiro Ogura, Akira Hiratsuka

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 349 KB

english, 2010

47

Enhanced sensitivity of A549 cells to the cytotoxic action of anticancer drugs via suppression of Nrf2 by procyanidins from Cinnamomi Cortex extract

Tomokazu Ohnuma, Takashi Matsumoto, Ayano Itoi, Ayako Kawana, Takahito Nishiyama, Kenichiro Ogura, Akira Hiratsuka

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 594 KB

english, 2011

48

Effects of smoking cessation on coronary endothelial function in patients with recent myocardial infarction

Shinobu Hosokawa, Yoshikazu Hiasa, Shinichiro Miyazaki, Riyo Ogura, Hitoshi Miyajima, Yoshikazu Ohara, Kenichiro Yuba, Naoki Suzuki, Takefumi Takahashi, Koichi Kishi, Ryuji Ohtani

Journal:

International Journal of Cardiology

Year:

2008

Language:

english

File:

PDF, 210 KB

english, 2008

49

Impaired motor functions in mice lacking the RNA-binding protein Hzf

Takatoshi Iijima, Hiroo Ogura, Kanako Takatsuki, Shigenori Kawahara, Kenichiro Wakabayashi, Daisuke Nakayama, Masato Fujioka, Yuki Kimura, Alan Bernstein, Hirotaka James Okano, Yutaka Kirino, Hideyuki

Journal:

Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

50

P3-29 THE EFFICACY OF SIROLIMUS-ELUTING STENT IMPLANTATION AFTER DIRECTIONAL CORONARY ATHERECTOMY

Po-Min Chen, Yoshikazu Hiasa, Yohei Tobetto, Shinichiro Miyazaki, Keitaro Mahara, Riyo Ogura, Hitoshi Miyajima, Kenichiro Yuba, Naoki Suzuki, Takefumi Takahashsi, Shinobu Hosokawa, Koichi Kishi, Ryuji

Journal:

International Journal of Cardiology

Year:

2007

Language:

english

File:

PDF, 429 KB

english, 2007

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